The answer is NO. And that too not even with the cheese. There aren’t any particular digestive mechanisms for pizza. If you really did cut back your consumption of everything else, the effect on fat storage would be nil.
You can have an allergy or sensitivity to dairy or gluten that would affect inflammation and fluid balance and put on some temporary weight, however.
If you eat less than or equal to the calories you burned that day, then your net calorie gain is zero or negative. No matter what you ate. However each person differs in how efficiently they digest food.
You can use a Basal Metabolic Rate calculator () to determine the calories your body burns while at rest. Exceeding that amount of calories without significant exercise will result in net gain.
You can burn 1,385 calories per day by just doing absolutely nothing. Experts say there are 2,497 calories in a 14″ pizza.
First off, the cheese isn’t going to be your problem unless you have some sort of pre-existing condition that makes cheese a problem for you.
Cheese is good. It’s full of good fat and protein. It’s not going to hurt your weight loss goals as long as you keep an eye on your macros (protein:fat:carb levels) and your calories.
The primary problem you run into is the sodium involved in pizza making and the white flour that makes up the crust.
Sodium in high doses, especially without enough water or potassium, causes all sorts of problems in the body, including making it more difficult to lose fat.
White flour is a problem because it is absorbed in the body with about the same speed as sugar. That causes insulin spikes, fat retention, and a generally crappy feeling.
Believe it or not, adding cheese to the pizza actually makes it more healthy. This is because that fat (and to some extent the protein) actually allows down the absorption of the simple carbs in the crust (because fat takes much longer to break down in your digestive system) , and somewhat reduces your fat retention and insulin variation.